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Physician Bio

  • Sumeet Mainigi, M.D.

    Dr. Mainigi is Associate Director of Electrophysiology at Einstein Medical Center as well as an assistant professor of medicine at Jefferson Medical College. He has specific expertise in ablation of atrial fibrillation, ventricular tachycardia, supraventricular tachycardias, and implantation of pacemakers, defibrillators, and biventricular-devices.

    Dr. Mainigi has presented original research at many national scientific meetings and has authored numerous publications in the fields of cardiology and electrophysiology, including a breakthrough catheter ablation study.

    Given the Outstanding Educator of the Year award by the Einstein House staff and Fellows, Dr. Mainigi has been recognized as a Top Doc by Philadelphia magazine. Additionally, his treatment of coronary disease with catheter ablation was listed as number twenty in the 2012 Top Docs issue's list of "28 Amazing New Ways Philly Doctors Can Save Your Life."

    Top Doc, 2008, Philadelphia magazine
    Top Doc, 2011, Philadelphia magazine
    Top Doc, 2012, Philadelphia magazine
    Top Doc, 2013, Philadelphia magazine 
    Top Doc, 2014, Philadelphia magazine

    Awards and Distinctions 

    • US News and World Reports – Top Doctor Cardiac Electrophysiology 2011
    • Philadelphia magazine – Top Doctors in Philadelphia – Cardiac Electrophysiology 2011, 2012
    • Philadelphia magazine  –  Top Doctor Under Age of 40/The Next Generation of Great Philly Docs 2009
    • Patient’s Choice Award for Top Physician 2008, 2009, 2010, 2011
    • Compassionate Doctor Award 2009, 2010, 2011
    • America’s Top Cardiologists 2009, 2011
    • Teaching Award, Division Of Cardiology, Einstein Medical Center
    • Herbert S. Waxman, M.D. Full-Time Faculty Teaching Award, Einstein Medical Center
    • Outstanding Educator of the Year, Einstein Medical Center

    Recent Research Projects and Publications

    • Mainigi SK, Almuti K, Figueredo VM, Guttenplan NA, Aouthmany A, Smukler J, Sheeron B, Meldrum B, Saenz AD, Tran G, Greenspan AM. Usefulness of Radiofrequency Ablation of Supraventricular Tachycardia to Reduce Inappropriate Shocks from Implantable Cardioverter-Defibrillators. The American Journal of Cardiology 2012;  109(2):231-7.
    • Rivas N, Dhruvakumar S, Mainigi SK, Smith T, Gerstenfeld EP, Marchlinski FE.  Ventricular Premature Depolarizations Triggered By Incremental Dose Isoproterenol Infusion: Common Electrocardiographic Features.  Journal of Interventional Cardiac Electrophysiology 2009; 25(1): 43-51)
    • Mohler ER, Sarov-Blat L, Shi Y, Hamamdzic D, Zalewski A, MacPhee C, Llano R, Pelchovitz D, Mainigi SK, Osman H, Hallman T, Steplewski K, Gertz Z, Lu MM, Wilensky RL.  Site-specific Atherogenic Gene Expression Correlates with Subsequent Variable Lesion Development in Coronary and Peripheral Vasculature. Atherosclerosis, Thrombosis, and Vascular Biology 2008; 28(5): 850-855. 
    • Mainigi SK, Sauer WH, Dixit S, Gerstenfeld EP, Callans DJ, Russo AM, Verdino RJ, Lin D, Cooper JM, Zado ES, Marchlinski FE. Late recurrence of atrial fibrillation after ablation is due to pulmonary vein reconnectivity and development of new pulmonary vein and non-pulmonary vein triggers. Journal of Cardiovascular Electrophysiology 2006; 18(1): 69-74.
    • Mainigi SK, Cooper JM, Russo AM, Nayak H, Lin D, Dixit S, Gerstenfeld EP, Hsia HH, Callans DJ, Marchlinski FE, Verdino RJ. Elevated defibrillation thresholds in patients undergoing biventricular defibrillator implantation: incidence and predictors.  Heart Rhythm 2006; 9(3): 1010-1016.
    • Mainigi SK, Goldberg LR, Sasseen B, See VY, Wilensky RL. Relative contributions of intimal hyperplasia and vascular remodeling in early cardiac transplant mediated coronary artery disease. The American Journal of Cardiology 2003; 91(3): 293-296.
    • Mehta V, Gupta S, Kao CK, Sheeron B, Greenspan A, Mainigi S. Incidence and Predictors of Recovery in Tachycardia-Induced Cardiomyopathy. Europace 2010; 12.
    • Greenspan A, Almuti K, Mainigi S. Potential Pro-Arrhythmic Effects of Implantable Devices. Journal of Cardiovascular Electrophysiology 2009; 20: S76.
    • Greenspan A, Almuti K, Mainigi S. Supraventricular Tachycardia Post Device Implants. Journal of Cardiovascular Electrophysiology 2009; 20: S95.
    • Ahlemeyer LM, Mainigi SK, Zado ES, Riley MP, Hutchinson MD, Bala R, Garcia FC, Lin D, Dixit S, Gerstenfeld EP, Verdino RJ, Russo AM, Callans DJ, Marchlinski FE, Cooper JM.  Low Cardioversion Success Rates in the Days Immediately Following Atrial Fibrillation Ablation.  Heart Rhythm 2008; 5(5): S357.
    • Hamamdzic D, Mainigi SK, Gertz ZM, Mohler III ER, Wilensky RL. The combination of diabetes mellitus and hypercholesterolemia in swine leads to the development of complex, human-like atherosclerosis.  Journal of the American College of Cardiology 2007; 49(9): 315A.
    • Mainigi SK, Sauer WH, Zado ES, Bazan V, Bindra PS, Riley MP, Gerstenfeld EP, Callans DJ, Marchlinski FE. Are cases of late recurrence of atrial fibrillation after ablation due to development of new triggers? Heart Rhythm 2006; 3(5): S325-S326.
    • Lin D, Gerstenfeld EP, Dixit S, Cooper JM, Mainigi SK, Zado E, Russo AM, Verdino RJ, Callans DJ, Marchlinski FE.  Efficacy of pulmonary vein isolation in patients with paroxysmal versus persistent atrial fibrillation. Heart Rhythm 2006; 3(5): S205.
    • Sauer WH, Mainigi SK, Hutchinson M, Sussman JS, Garcia FC, Bala R, Verdino RJ, Russo AM, Marchlinski FE, Cooper JM. Normalization of Left Ventricular Ejection Fraction after Cardiac Resynchronization Therapy is More Frequent in Patients with Non-Ischemic Cardiomyopathy. Journal of the American College of Cardiology 2006; 47(4): 22A.
    • Sauer WH, Hutchinson M, Mainigi SK, Toca M, Ilkhanoff L, Bindra P, Riley MP, Gerstenfeld EP, Callans DJ, Marchlinski FE, Cooper JM. Left Ventricular Lead Positioning over Infarcted Myocardium Results in Less Improvement in Ejection Fraction in Patients with Ischemic Cardiomyopathy and Cardiac Resynchronization Therapy. Journal of the American College of Cardiology 2006; 47(4): 12A.
    • Mainigi SK,  Mohler E, Osman H, Duwe B, Wilensky RL. Observations of a Large Animal Model of Diabetic Vascular Disease. Circulation Supplement 2004; 110 (17): III-706.
    • Mainigi SK, Garnes J, Goldman ME.  Does Multiplane Transesophageal Echo have a Greater Clinical Impact than Biplane?  Journal of the American Society of Echocardiography. 1999; 12(5):376.
    • Goldman ME, Mainigi SK.  Value of Transesophageal Echo (V.O.T.E.): A Multicenter International Registry of 8500 Patients from 21 Sites.  Journal of the American College of Cardiology Supplement 1998; 31(2): 162A. 

    Locations & Hours

    The Hosp. of the University/PA


    The Hosp. of the University/PA

    Medical School

    New York University Sch of Med


    The Hosp. of the University/PA

    Board Certifications
    • Cardiology
    • Electrophysiology
    Takes Referrals for:
    • Cardiology
    • Electrophysiology
    Areas of Interest
    • Pacemaker Insertion
  • Sumeet Mainigi