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LARONIDASE (la RON i daz) is a drug that is used to replace an enzyme that is missing in patients with some forms of mucopolysaccharidosis I (MPS I). It is used to treat some of the symptoms of the disease. This medicine is not a cure.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
an unusual or allergic reaction to laronidase, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months old for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Your condition will be monitored carefully while you are receiving this medicine.
Visit your doctor for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
There is a registry for MPS I patients to better understand the disease and the treatments. Talk to your doctor about signing up with the registry.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
swelling of feet or hands
low blood pressure
pain, tingling, numbness in the hands or feet
redness, pain, or swelling at site where injected
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
irritation at site where injected
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This drug is given in a hospital or clinic and will not be stored at home.