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PASIREOTIDE (PAS i REE oh tide) is used to reduce blood levels of cortisol in patients with a condition called Cushing's disease. It is used when surgery is not an option or has not worked well enough.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
history of irregular heartbeat
history of pancreatitis
low levels of magnesium or potassium in the blood
an unusual or allergic reaction to pasireotide, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This medicine is for injection under the skin. You will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
beta-blockers like metoprolol and propranolol
calcium channel blockers like diltiazem and verapamil
certain antibiotics like clarithromycin, erythromycin, telithromycin
medicines for depression called tricyclic antidepressants
medicines for fungal infections like itraconazole, ketoconazole, voriconazole
medicines for malaria like chloroquine and halofantrine
medicines to control heart rhythm like amiodarone, disopyramide, flecainide, ibutilide, quinidine, propafenone, sotalol
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
You may need blood work done while you are taking this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heartbeat
feeling faint or lightheaded, falls
increased hunger or thirst
loss of appetite
right upper belly pain
unusually slow heartbeat
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
pain, redness, or irritation at site where injected
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store this medicine at room temperature between 20 to 25 degrees C (68 to 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date on the label.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.