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The duodenum is the first part of the small intestine, just past the stomach. Your health care provider thinks that you may have duodenitis. This is inflammation of the lining of the duodenum. This sheet tells you more about the condition.
The most common cause of duodenitis is infection by Helicobacter pylori (H. pylori) bacteria. Another common cause is long-term use of NSAIDs (such as aspirin and ibuprofen). Less commonly, duodenitis occurs along with another health problem, such as Crohn’s disease. Drinking alcohol, smoking, or taking certain medications also may make duodenitis more likely to occur.
The condition may cause no symptoms. If symptoms do occur, they can include:
Burning, cramping, or hunger-like pain in your stomach
Gas or a bloated feeling
Nausea and vomiting
Feeling full soon after starting a meal
If duodenitis is suspected, an upper endoscopy with biopsy will be done to confirm it. During this test, a thin, flexible tube with a light and camera on the end (endoscope) is used. The scope is moved down your throat to the stomach and into the duodenum. The scope sends images of the duodenum to a video screen. Small samples (biopsy) of the lining of the duodenum may be taken. These samples are sent to a lab for testing for H. pylori.
To check for H. pylori or other pathogens, a blood, stool, gastric biopsy, or breath test may be done. Samples of blood or stool are taken and tested in a lab. For a breath test, you swallow a harmless compound. If H. pylori bacteria are present, extra carbon dioxide gas can then be detected in your breath.
In rare cases, an upper gastrointestinal (GI) series is done. This gives more information about the digestive tract. This procedure takes x-rays of the upper GI tract from the mouth to the small intestine.
Duodenitis is treated using one or more of the following:
Antibiotic medications to kill H. pylori
Medications to reduce the amount of acid the stomach makes
Stopping NSAIDs such as aspirin and ibuprofen
Your health care provider can tell you more about what treatments are needed.
With treatment, most cases of duodenitis clear up completely. In rare cases, duodenitis can be an ongoing (chronic) problem or can develop into a duodenal ulcer. If your symptoms do not improve or if they go away and come back, let your health care provider know. In such cases, regular health care provider visits and treatments are needed to manage your condition.
Call your doctor right away if you have any of the following:
Fever of 100.4°F (38.0°C) or higher
Nausea or vomiting (vomit may be bloody or look like coffee grounds)
Dark, tarry, or bloody stools
Sudden or severe abdominal pain
Pain that does not improve with treatment
Rapid weight loss