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CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked. This medicine in only available from your doctor, who must register with the drug company and meet certain criteria for the use of this drug. This medicine has not been available in pharmacies since August 2000. For information, the manufacturer has provided the following toll-free number (877) 795-4247.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
eating disorder, like anorexia or bulimia
heart disease or heart failure
heart rhythm problems
heart valve problems
history of low levels of calcium, potassium, or magnesium
stomach bleeding, blockage, or ulceration
an unusual or allergic reaction to cisapride, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take this medicine on an empty stomach, at least 15 minutes before eating and at bedtime. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
certain antibiotics like ciprofloxacin, clarithromycin, dalfopristin;quinuprostin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, sparfloxacin, telithromycin or troleandomycin
certain medicines for cancer like daunorubicin and doxorubixin
general and local anesthetics
medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, or voriconazole
medicines for treating HIV infection or AIDS
medicines for treating depression, psychosis, or other mental problems
medicines used to treat erectile dysfunction (ED) like sildenafil, tadalafil, and vardenafil
phenothiazines like chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine
some medicines for treating heart-rhythm problems like amiodarone, disopyramide, bretylium, dofetilide, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol
This medicine may also interact with the following medications:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress. For this medicine to work properly it is important to make lifestyle changes. Eat smaller meals, elevate the head of your bed 6 to 8 inches, avoid high-fat foods, chocolate, alcohol, smoking, caffeine and carbonated drinks.
If you have any fainting spells or rapid or irregular heartbeat, stop taking this drug immediately. Contact your health care professional right away for evaluation.
Do not drink grapefruit juice while you are taking this medicine. Grapefruit juice could increase your risk of having serious side effects from this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
feeling faint or lightheaded, falls
rapid or irregular heartbeat
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea or constipation
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked. This medicine in only available from your doctor, who must register with the drug company and meet certain criteria for the use of this drug. Cisapride has not been available in pharmacies since August 2000. For information, the manufacturer has provided the following toll-free number (877) 795-4247.
Take this medicine by mouth with a glass of water. Follow the directions on the label. Take this medicine on an empty stomach, at least 15 minutes before eating and at bedtime. Do not take your medicine more often than directed.
certain medicines for cancer like daunorubicin and doxorubicin
medicines for fungal infections like ketoconazole and itraconazole
medicines for HIV
medicines for depression, anxiety, or psychotic disturbances
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
some medicines for treating heart-rhythm problems
fainting or falling spells