Skip to main content
More Search Options
A member of our team will call you back within one business day.
NAPROXEN; SUMATRIPTAN (na PROS en; soo ma TRIP tan) is used to treat migraines with or without aura. An aura is a strange feeling or visual disturbance that warns you of an attack. This medicine is not used to prevent migraines.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
hemiplegic or basilar migraine
high blood pressure
if you frequently drink alcohol containing drinks
ischemic bowel disease
low blood counts, like low white cell, platelet, or red cell counts
lung or breathing disease, like asthma
peripheral vascular disease like intermittent claudication
take medicines that treat or prevent blood clots
taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
an unusual or allergic reaction to Naproxen; Sumatriptan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not cut, crush, or chew this medicine. Do not take it more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
This does not apply; this medicine is not for regular use.
What drug(s) may interact with Naproxen; Sumatriptan?
Do not take this medicine with any of the following medications:
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
This medicine may also interact with the following medications:
angiotensin-converting enzyme inhibitors (ACE inhibitors) like captopril, enalapril, lisinopril, and ramipril
aspirin and aspirin-like medicines
medicines for blood pressure like amlodipine, felodipine, nifedipine
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
selective serotonin reuptake inhibitors such as citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline
steroid medicines like prednisone or cortisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Only use this medicine for a migraine headache. Use it if you get warning symptoms or at the start of a migraine attack. This medicine is not for regular use to prevent migraine headaches. Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Do not take other medicines that contain aspirin, ibuprofen, or naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.
This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth. If you have any dental work done, tell your dentist you are receiving this medicine.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
changes in vision
confusion, trouble speaking or understanding
fast, irregular heartbeat
feeling of chest heaviness or pressure
general ill feeling or flu-like symptoms
redness, blistering, peeling or loosening of the skin, including inside the mouth
swelling of the ankles, feet, hands
severe stomach pain
slurred speech or weakness on one side of the body
sudden numbness or weakness of the face, arm or leg
tingling, pain, or numbness in the face, hands or feet
trouble walking, dizziness, loss of balance or coordination
unusual bleeding or bruising
unusually weak or tired
yellowing of eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.