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AMILORIDE; HYDROCHLOROTHIAZIDE (a MIL oh ride; hye droe klor oh THYE a zide) is a combination of two types of diuretics. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure and heart failure.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
immune system problems, like lupus
small amount of urine
unusual or allergic reaction to amiloride, hydrochlorothiazide, other diuretics, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
potassium sparing diuretics
This medicine may also interact with the following medications:
ACE inhibitors for heart or kidney disease like captopril, lisinopril
antiinflammatory drugs, NSAIDs like ibuprofen
barbiturate medicines for sleep or seizure control
medicines for diabetes
medicines for high blood pressure or heart failure
neuromuscular blockers used during surgery
some medicines for pain like codeine
steroid hormones like cortisone, hydrocortisone, prednisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor what your blood pressure should be, and when you should contact them. If you are diabetic, check your blood sugar as directed.
You may need to be on a special diet while taking this medicine. Ask your doctor. You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black or tarry stools
changes in vision
fast, irregular heartbeat
feeling faint or lightheaded, falls
muscle pain, cramps
numbness, tingling in hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
trouble passing urine or change in the amount of urine
unusually weak or tired
worsened gout pain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
dry mouth, increased thirst
enlarged, tender breasts
irregular menstrual periods
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.