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APREPITANT (ap RE pi tant) is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy). It is also used alone to prevent nausea and vomiting caused by anesthesia used during surgery.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
an unusual or allergic reaction to aprepitant, fosaprepitant, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Usually, you will take your first dose one hour before your chemotherapy begins, and then once daily in the morning for the next 2 days after your chemotherapy treatment. This medicine may be taken with or without food. Do not take more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of these medicines:
This medicine may also interact with the following medications:
female hormones, like estrogens or progestins and birth control pills
medicines for fungal infections like ketoconazole and itraconazole
medicines for HIV
medicines for seizures or to control epilepsy like carbamazepine or phenytoin
medicines used for sleep or anxiety disorders like alprazolam, diazepam, or midazolam
some chemotherapy medications like etoposide, ifosfamide, vinblastine, vincristine
some antibiotics like clarithromycin, erythromycin, troleandomycin
steroid medicines like dexamethasone or methylprednisolone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Do not take this medicine if you already have nausea and vomiting. Ask your health care provider what to do if you already have nausea.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.
This medicine should not be used continuously for a long time.
Visit your doctor or health care professional for regular check-ups. This medicine may change your liver function blood test results.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in heart rhythm
high or low blood pressure
serious dizziness or disorientation, confusion
sharp or severe stomach pain
sharp pain in your leg
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation or diarrhea
loss of appetite
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
FOSAPREPITANT (fos ap RE pi tant) is used together with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy).
an unusual or allergic reaction to fosaprepitant, aprepitant, medicines, foods, dyes, or preservatives
This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.
This does not apply.
pain, redness, or irritation at site where injected
This drug is given in a hospital or clinic and will not be stored at home.