Blood can be broken down into different parts that perform special roles in the body. These parts include:
Except for self-donated blood, all donated blood is tested and processed to make sure that the blood is safe:
A blood transfusion takes place in a blood center, hospital room, or operating room. It usually lasts 1–2 hours. Your health care provider will discuss the blood transfusion with you before it’s done. You’ll need to give permission for the blood transfusion by signing a consent form.
Most transfusions are problem free. In some cases, reactions occur. These can happen within seconds to minutes during the transfusion or a week to a few months after the transfusion. Call your doctor or nurse right away if you have any of the signs or symptoms in the table below during or after a transfusion:
Reaction | Timing | Signs and Symptoms |
Allergic Reaction (mild) | | Hives or red welts on the skin, mild itching, rash, localized swelling. flush (red face), wheezing, shortness of breath, or stridor (high pitch noise or sound) |
Anaphylactic Reaction | | Shortness of breath, flushing (red face), wheezing, labored (working hard) breathing, low blood pressure, localized swelling, chest tightness, or cramps |
Febrile Nonhemolytic Reaction | | Fever (increased of 1° C or higher), chills, flushing (red face), nausea, headahce, minor discomfort, o rmild shortness of breath |
Acute Immune Hemolytic Reaction | | Fever, red or brown urine, back pain, fast heart rate (tachycardia), abdominal pain, low blood pressure, feeling anxious, chills, chest pain, nausea, or fainting spells |
Transfusion-Related Acute Lung Injury (TRALI) | | Shortness of breath, trouble breathing, low blood pressure, fever, pulmonary edema |
Transfusion-Associated Circulatory Overload | | Shortness of breath, fast heart rate (Tachycardia), problems breathing when lying on back, abnormal blood pressure |
Post-Transfusion Purpura (PUP) | | Purple spots on skin, nose bleed, urinary tract, abdomen, colon, or rectum, fever, or chills |
"Delayed" Transfusion-Related Acute Lung Injury (TRALI) | | "Sudden" onset of respiratory distress or trouble breathing |
"Delayed" Hemolytic Reaction | | Low grade fever, mild jaundice (yellowing of the skin and whites of the eyes), decrease in hematocrit, chills, chest pain, back pain, nausea |