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Polio and Mobility

Polio and Mobility

Assessment and Treatment of Shoulder Dysfunction in Post-Polio and Elderly Populations -- Part I

What's New in Polio and Mobility Research at MRRI
Our recent publication "Save Our Shoulders: A Guide for Polio Survivors" is now available for download.
Click here to view or download this brochure (1.48mb PDF file)
For more information on Polio and Mobility Research, call the Polio and Mobility research office at
(215) 456-4993
Mary Klein, PhD, Principal Investigator;
Alberto Esquenazi, MD; Mary Ann Keenan, MD, Co-investigators

Shoulder pain is common in the post-polio population. Similar symptom patterns are seen in older adults who have no history of polio, but who do have lower extremity impairments. The shoulder pain is thought to result from repetitive use of the arms to assist with weight-bearing during mobility and transfer activities when there is significant weakness in one or more of the muscles in the lower extremities. The increased stress on the upper extremities during these activities results in symptoms of shoulder overuse. Currently, there is controversy as to whether a strengthening program will be an effective treatment for shoulder overuse in ambulatory people with disabilities and whether the treatment for shoulder overuse in these individuals should be directed at the lower and /or upper extremities.

In this project, subjects with shoulder pain potentially attributable to overuse will participate in a 16-week treatment program. Subjects will be randomly assigned to either an exercise group or a relaxation therapy group. Each member of the exercise group will receive an individualized program that includes exercises for both the upper and lower extremities, while the members of the relaxation therapy group will be taught techniques for reducing stress. Researchers will also collect data on pain, strength, activity level and health-related quality of life. The objective of this project is to determine whether physicians can recommend exercise to effectively treat upper-extremity overuse problems in ambulatory people with lower-extremity disabilities.


Treatment of Shoulder Dysfunction in Polio Survivors and Elder Adults with Lower- Extremity Impairment -- Part II

Mary Klein, PhD, Principal Investigator; Alberto Esquenazi, MD; Mary Ann Keenan, MD, Co-investigators

In our previous research on polio survivors, we determined that shoulder pain was one of the most frequent overuse symptoms seen in the post-polio population. We developed a predictive model of shoulder pain that demonstrated that lower-extremity weakness and weight were associated with the presence of shoulder overuse symptoms. This suggested that these symptoms may arise from use of the upper extremities to compensate for lower-extremity weakness during mobility-related tasks like transferring from a sitting position to a standing position. Although numerous articles have been published on the importance of exercise and physical activity in promoting health and preventing disease, there are still many unanswered questions about whether exercise can be used to effectively treat or even prevent the development of secondary disabilities, particularly those related to overuse.

In this project, subjects with shoulder pain potentially attributable to overuse will be randomly assigned to one of two 16-week exercise programs. One program will involve exercises for the upper extremities only and the other will involve exercise for the lower extremities only. Data on the changes in shoulder symptoms, strength, and activity level will be collected. Subjects will also undergo a detailed evaluation of their behavior and muscle activity in the Gait and Motion Analysis Lab. The objective is to determine whether the strengthening program resulted in a reduction of the upper-extremity loading or the stress on the arms due to weight-bearing during a chair rise task.

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